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Volume 358:1870-1871 April 24, 2008 Number 17
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Two Doses of Azithromycin to Eliminate Trachoma in a Tanzanian Community

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by Cook, J. A.
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To the Editor: Single-dose azithromycin is the first-choice antibiotic for the treatment of trachoma. The World Health Organization (WHO) currently recommends annual mass azithromycin treatment for 3 years in communities in which the prevalence of the clinical sign "trachomatous inflammation–follicular" in children between 1 and 9 years of age is 10% or more.

We previously reported the effect of high-coverage, single-dose mass azithromycin treatment on ocular Chlamydia trachomatis infection in Kahe Mpya, Tanzania.1 In all, 97.6% of residents were treated; the prevalence of ocular C. trachomatis fell from 9.5% at baseline to 0.1% 24 months later. We subsequently carried out . . . [Full Text of this Article]



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