FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 358:2172-2174 May 15, 2008 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Zethelius, B. PubMed Citation

Guidelines for the assessment of cardiovascular risk remain focused squarely on established risk factors.¹ Although it is known that tools based on these risk factors, such as the Framingham Risk Score, have a number of limitations when applied in clinical practice — performing reasonably well for groups but not necessarily for individuals and underestimating long-term risk among younger persons² — it has proved surprisingly difficult to improve on established risk factors for the prediction of cardiovascular disease. Of the many strategies that have been proposed to improve risk stratification, the measurement of plasma biomarkers is particularly attractive as compared with . . . [Full Text of this Article]

Source Information

From the Donald W. Reynolds Cardiovascular Clinical Research Center, University of Texas Southwestern Medical Center, Dallas (J.A.L.); and the Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago (D.M.L.-J.).

This article has been cited by other articles:

• Greco, T. P., Conti-Kelly, A. M., Greco, T. Jr, Doyle, R., Matsuura, E., Anthony, J. R., Lopez, L. R. (2009). Newer Antiphospholipid Antibodies Predict Adverse Outcomes in Patients With Acute Coronary Syndrome. Am J Clin Pathol 132: 613-620 [Abstract] [Full Text]  
• Melander, O., Newton-Cheh, C., Almgren, P., Hedblad, B., Berglund, G., Engstrom, G., Persson, M., Smith, J. G., Magnusson, M., Christensson, A., Struck, J., Morgenthaler, N. G., Bergmann, A., Pencina, M. J., Wang, T. J. (2009). Novel and Conventional Biomarkers for Prediction of Incident Cardiovascular Events in the Community. JAMA 302: 49-57 [Abstract] [Full Text]  
• Shah, S. H., de Lemos, J. A. (2009). Biomarkers and Cardiovascular Disease: Determining Causality and Quantifying Contribution to Risk Assessment. JAMA 302: 92-93 [Full Text]  
• (2008). Cardiovascular Risk Prediction: Beyond the Established Risk Factors. Journal Watch Cardiology 2008: 3-3 [Full Text]