FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 358:2412-2413 May 29, 2008 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Rahman, A. PubMed Citation

To the Editor: In their review article, Rahman and Isenberg (Feb. 28 issue)¹ emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.² Interestingly, 36% of patients with type 1 autoimmune hepatitis and antibodies against double-stranded DNA have the HLA allele DR3, which is a genetic risk factor in both systemic lupus erythematosus and type 1 autoimmune hepatitis.³ However, there is no evidence of a pathogenic role of anti–double-stranded DNA antibodies in type 1 autoimmune . . . [Full Text of this Article]

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.