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Correspondence
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Volume 358:2414-2415 May 29, 2008 Number 22
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Cortical Arousal in Children with Severe Enuresis

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To the Editor: Children with nocturnal enuresis are generally believed to be deep sleepers with impaired arousability.1 However, there are conflicting data with regard to sleep patterns in children with enuresis.2,3 Nocturnal enuresis often occurs with unstable bladder contractions in conjunction with polysomnographic changes from deep sleep to lighter sleep but without full awakening,4 suggesting that a relationship may exist between bladder overactivity and deranged arousability. We therefore investigated sleep patterns and cortical arousal in relation to bladder activity in children with severe enuresis.

Children with primary nocturnal enuresis that was severe and refractory (≥5 wet nights per week) . . . [Full Text of this Article]



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