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Volume 358:2840-2842 June 26, 2008 Number 26
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Red-Cell Storage and Complications of Cardiac Surgery

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by Koch, C. G.
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To the Editor: Koch et al. (March 20 issue)1 report increased risks of postoperative complications and death among patients undergoing cardiac surgery who were given blood that had been stored for more than 2 weeks, as compared with those given newer blood. These results are similar to those in a recently reported study; in that study, however, risk adjustment for confounding influences negated the storage effect.2 Koch et al. present predominantly non–risk-adjusted data, despite significant group differences. Risk-adjusted data are reported only for an inadequately described composite outcome, with greatly diminished significance (unadjusted P=0.001; adjusted odds ratio, 1.16 [95% confidence . . . [Full Text of this Article]



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