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Volume 358:306-307 January 17, 2008 Number 3
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Prednisolone or Acyclovir in Bell's Palsy

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 by Gilden, D. H.
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 by Sullivan, F. M.
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To the Editor: Sullivan et al. (Oct. 18 issue)1 report that early treatment with prednisolone significantly improves the chances of complete recovery in patients with Bell's palsy, whereas no evidence of a benefit of acyclovir could be found. Idiopathic peripheral-facial-nerve paralysis of sudden onset is difficult to diagnose because other causes that are associated with a significantly higher risk of defective healing2 must be ruled out. Since zoster sine herpete — which can mimic the signs and symptoms of Bell's palsy — caused by varicella–zoster virus has an incidence rate of up to 34% among patients with "Bell's palsy,"3 information . . . [Full Text of this Article]




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