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Editorial
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Volume 358:405-407 January 24, 2008 Number 4
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Drug-Eluting Stents — Pushing the Envelope beyond the Labels?
Joseph P. Carrozza, Jr., M.D.

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 by Marroquin, O. C.
-PubMed Citation
Unlike jurors, clinicians frequently must make decisions without the luxury of the totality of evidence. When we speak of evidence-based medicine, it is important to remember that available data may be incomplete, outdated, and of questionable relevance to particular patients, especially those excluded from randomized trials. Nowhere is this more apparent than in the controversies surrounding the use of drug-eluting stents in patients with coronary disease.

Pivotal trials of drug-eluting stents reported significant reductions in the rate of repeat revascularization without excess adverse events in the first year after placement of the stent.1,2 Although these randomized trials were well designed . . . [Full Text of this Article]


Source Information

From Harvard Medical School and the Cardiovascular Division, Beth Israel Deaconess Medical Center — both in Boston.


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