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Previous Volume 358:615-624 February 7, 2008 Number 6 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

A 65-year-old man reports a 6-month history of dizziness, light-headedness, weakness, and fatigue while upright. He takes no medication and has no personal or family history of neurologic disease. On physical examination, his supine blood pressure is 160/100 mm Hg, with a heart rate of 72 beats per minute; on standing, his blood pressure falls to 70/40 mm Hg, with no change . . . [Full Text of this Article]

The Clinical Problem

Physiological and Clinical Features

Causes of Neurogenic Orthostatic Hypotension

Strategies and Evidence

Evaluation

Treatment

            Nonpharmacologic Interventions

            Pharmacologic Interventions

Areas of Uncertainty

Guidelines from Professional Societies

Conclusions and Recommendations

Source Information

From the Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston.

Address reprint requests to Dr. Freeman at the Center for Autonomic and Peripheral Nerve Disorders, Department of Neurology, Beth Israel Deaconess Medical Center, 1 Deaconess Rd., Boston, MA 02215, or at rfreeman@bidmc.harvard.edu.

Related Letters:

Neurogenic Orthostatic Hypotension
Joy M., Freeman R.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:2298, May 22, 2008. Correspondence

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