Recently, the potential use of stem cells for regenerative medicineand for the treatment of genetic disease has rarely been outof the news. Discussion has focused mainly on the use of humanembryonic stem cells, which in culture have the capacity togenerate all cell types. However, initial hopes for stem-celltherapy have been somewhat dampened by both technical and ethicalproblems. Recent studies have therefore created a great dealof excitement. They show that fully differentiated somatic cells(such as skin fibroblasts) can be reprogrammed to make cellssimilar to embryonic stem cells, called induced pluripotentstem cells.1. . . [Full Text of this Article]
Source Information
From Weatherall Institute of Molecular Medicine, Medical Research Council Molecular Haematology Unit, John Radcliffe Hospital, Oxford, United Kingdom.
This article has been cited by other articles:
Pomerantz, J. H., Mukherjee, S., Palermo, A. T., Blau, H. M.
(2009). Reprogramming to a muscle fate by fusion recapitulates differentiation. J. Cell Sci.
122: 1045-1053
[Abstract][Full Text]