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Previous Volume 359:1178-1180 September 11, 2008 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Hutchison et al. (June 5 issue)¹ report that hypothermia therapy that was initiated within 8 hours after traumatic brain injury and continued for 24 hours did not improve the neurologic outcome in children in their study. However, five meta-analyses of hypothermia therapy in adults with traumatic brain injury showed a reduction of 22 to 39% in the risk of a poor outcome,² and the differences in two of these studies were significant.^3,4

Hypothermic neuroprotection crucially depends on the promptness⁵ and duration² of treatment (since brain edema peaks 1 to 4 days after such injury), as well as . . . [Full Text of this Article]

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