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Editorial
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Volume 359:1618-1620 October 9, 2008 Number 15
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UKPDS and the Legacy Effect
John Chalmers, M.D., Ph.D., and Mark E. Cooper, M.D., Ph.D.

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-Related Article
 by Holman, R. R.
-Related Article
 by Holman, R. R.
-PubMed Citation
The United Kingdom Prospective Diabetes Study (UKPDS) continues to produce important evidence concerning the evolution of type 2 diabetes and its management. Two studies published in this issue of the Journal provide some answers to two questions of fundamental importance to patients with diabetes and to physicians alike. In one article, Holman et al. (UKPDS 80)1 provide data that confirm a so-called legacy effect associated with intensive glucose control in patients with type 2 diabetes, long after the cessation of randomized intervention. This finding provides a fitting parallel to the observations of the Diabetes Control and Complications Trial/Epidemiology of Diabetes . . . [Full Text of this Article]


Source Information

From the George Institute for International Health, University of Sydney, Sydney (J.C.); and the Baker IDI Heart and Diabetes Institute, Melbourne (M.E.C.) — both in Australia.


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