The United Kingdom Prospective Diabetes Study (UKPDS) continuesto produce important evidence concerning the evolution of type2 diabetes and its management. Two studies published in thisissue of the Journal provide some answers to two questions offundamental importance to patients with diabetes and to physiciansalike. In one article, Holman et al. (UKPDS 80)1 provide datathat confirm a so-called legacy effect associated with intensiveglucose control in patients with type 2 diabetes, long afterthe cessation of randomized intervention. This finding providesa fitting parallel to the observations of the Diabetes Controland Complications Trial/Epidemiology of Diabetes . . . [Full Text of this Article]
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From the George Institute for International Health, University of Sydney, Sydney (J.C.); and the Baker IDI Heart and Diabetes Institute, Melbourne (M.E.C.) — both in Australia.
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