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Volume 359:1624-1625 October 9, 2008 Number 15
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Vasopressors in Cardiopulmonary Resuscitation

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 by Gueugniaud, P.-Y.
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To the Editor: Gueugniaud et al. (July 3 issue)1 report that administering the combination of vasopressin and epinephrine, as compared with epinephrine alone, during advanced cardiac life support for out-of-hospital cardiac arrest does not improve outcome. The results of this study, however, are not surprising, considering that the average time from collapse to the arrival of advanced cardiac life support (downtime) was 16.3 minutes in each group and that only 9% of the patients in each group had ventricular fibrillation and thus a greater chance of survival than the patients with pulseless electrical activity or asystole. Studies have shown that . . . [Full Text of this Article]


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