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Previous Volume 359:2065-2066 November 6, 2008 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The key issue regarding monoclonal B-cell lymphocytosis (MBL) and early chronic lymphocytic leukemia (CLL) is whether there is a fundamental biologic difference that influences the risk of progression and clinical management. Rawstron et al. (Aug. 7 issue)¹ analyzed follow-up data for 185 patients, all of whom presented with lymphocytosis. Most of them would have been classified as having early stage A CLL until the recent publication of revised guidelines,² and hence, features in common would be expected. The rate of progression from stage A to stage B or C is 10% over a period of 5 years . . . [Full Text of this Article]

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