FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 359:2166-2168 November 13, 2008 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Talmor, D. PubMed Citation

Treatment of the acute respiratory distress syndrome (ARDS) with positive end-expiratory pressure (PEEP) was introduced more than 40 years ago.^1,2 Few practitioners question the effects of PEEP on hemoglobin saturation, but the optimal dose titration is controversial. Usually PEEP is simply adjusted to a suitable increase in oxygenation efficiency (i.e., the ratio of the partial pressure of arterial oxygen [PaO₂] to the fraction of inspired oxygen [FiO₂]) or according to an algorithm such as the Acute Respiratory Distress Syndrome Network (ARDSNet) protocol.³ Because PEEP can impair cardiac output, some clinicians advocate titration to maximal oxygen delivery, a method . . . [Full Text of this Article]

Source Information

This article (10.1056/NEJMe0806637) was published at www.nejm.org on November 11, 2008.

From the Department of Medicine, Vanderbilt University School of Medicine, Nashville.

This article has been cited by other articles:

• (2008). Finding the Optimal PEEP for Patients with ARDS. JWatch Emergency Med. 2008: 2-2 [Full Text]