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Previous Volume 359:2579-2585 December 11, 2008 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.

In February 2007, fever developed in a previously healthy 15-year-old girl, with a peak temperature of 102°F (38.9°C) and mild upper respiratory congestion. The next day she was seen by her primary care physician. A rapid screening test for group A streptococcus was negative, and oseltamivir was prescribed. After two doses, she continued to have fever and also had nausea and emesis, . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Priorities for Vaccination

Composition and Distribution of Influenza Vaccine

Efficacy of the Vaccine

Case Management

Who Should Be Treated?

Antiviral Treatments

Areas of Uncertainty

Guidelines

Conclusions and Recommendations

Source Information

From the Departments of Molecular Virology and Microbiology and of Pediatrics, Baylor College of Medicine, Houston.

An audio version of this article is available at www.nejm.org.

Address reprint requests to Dr. Glezen at the Departments of Molecular Virology and Microbiology and of Pediatrics, Baylor College of Medicine, 1 Baylor Plaza, MS:BCM-280, Houston, TX 77030, or at wglezen@bcm.edu.

This article has been cited by other articles:

• Mossad, S. B. (2009). Influenza in long-term care facilities: Preventable, detectable, treatable. Cleveland Clinic Journal of Medicine 76: 513-521 [Abstract] [Full Text]