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Volume 359:888-890 August 28, 2008 Number 9
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An HIV Vaccine — Challenges and Prospects
Margaret I. Johnston, Ph.D., and Anthony S. Fauci, M.D.

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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 by Steinbrook, R.

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Now well into the third decade of the pandemic of human immunodeficiency virus (HIV) and AIDS, we have seen dramatic successes in the treatment of HIV-infected persons in the United States and many other countries. Yet the pandemic still rages, with 2.7 million new infections in 2007. Indeed, for every infected person who began receiving antiretroviral therapy in 2007, 2.5 people were newly infected with HIV. Historically, vaccines have been among the most effective public health interventions, preventing the spread of viral infections. But an HIV vaccine has thus far been elusive and the quest disappointing and frustrating, prompting some . . . [Full Text of this Article]


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Dr. Johnston is the director of the Vaccine Research Program in the Division of AIDS, National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD, and Dr. Fauci is the director of NIAID.

An interview with Anthony Fauci is available at www.nejm.org


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