In this issue of the Journal, Sankaranarayanan et al.1 reportthe results of a randomized clinical trial of screening forcervical cancer involving more than 130,000 women in India.The authors conclusively showed that a single round of screeningfor human papillomavirus (HPV) dramatically reduced the incidenceof advanced cervical cancer and cervical-cancer mortality within8 years far more than a single conventional cytologic test orvisual inspection of the cervix with acetic acid (VIA).
The implications of the findings of this trial are immediateand global: international experts in cervical-cancer preventionshould now adapt HPV testing for widespread implementation.. . . [Full Text of this Article]
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From the Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD.
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