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Volume 360:1673-1676 April 16, 2009 Number 16
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Oral Corticosteroids in Children with Wheezing

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by Bush, A.
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by Panickar, J.
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To the Editor: Panickar et al. (Jan. 22 issue)1 conclude that oral prednisolone is not effective for virus-induced wheezing, and the accompanying editorial states that "it is clear that on the basis of [this study], current practice must change."2 I disagree. The prednisolone group fared better clinically than the placebo group with respect to both the primary outcome (Table 2 of the article) and the secondary outcomes (Table 3 of the article). As compared with the prednisolone group, almost 50% more patients in the placebo group were still in the hospital after 24 hours, and the number of albuterol actuations . . . [Full Text of this Article]



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