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Clinical Therapeutics
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Volume 360:1749-1758 April 23, 2009 Number 17
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Minimally Invasive Total Knee Arthroplasty for Osteoarthritis
Seth S. Leopold, M.D.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

A 65-year-old woman with osteoarthritis of her right knee is referred by her primary care physician for orthopedic consultation. She is healthy except for some well-controlled hypertension. She is 5 ft 5 in. tall (165 cm) and weighs 160 . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and the Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations


Source Information

From the Department of Orthopedics and Sports Medicine, University of Washington School of Medicine, Seattle.

Address reprint requests to Dr. Leopold at the Department of Orthopedics and Sports Medicine, University of Washington School of Medicine, Box 356500, Seattle, WA 98195, or at leopold@u.washington.edu.


Related Letters:

Minimally Invasive Total Knee Arthroplasty
Kashyap A. S., Anand K. P., Kashyap S., Moneypenny M. J., Mercer S. J., Longo U. G., Maffulli N., Denaro V., Leopold S. S.
Extract | Full Text | PDF  
N Engl J Med 2009; 361:633-634, Aug 6, 2009. Correspondence

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