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Case Records of the Massachusetts General Hospital
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Volume 360:2341-2351 May 28, 2009 Number 22
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Case 17-2009 — A 30-Year-Old Man with Progressive Neurologic Deficits
David M. Greer, M.D., M.A., Robert P. Friday, M.D., Ph.D., Javier Romero, M.D., and Pavan K. Auluck, M.D., Ph.D.

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Presentation of Case

Dr. Katharina Busl (Neurology): A 30-year-old man was admitted to this hospital because of progressive neurologic deficits.

Approximately 1 year before this admission, he began to have intermittent headaches and the gradual onset of difficulty with word finding and writing, without changes in cognition, memory or personality, or sensorimotor deficits. Ten months before this admission, magnetic resonance imaging (MRI) of the brain, performed after the administration of gadolinium, showed enhancement of the genu and rostrum of the corpus callosum, and T2-weighted signal abnormality in the white matter and cortex of the left frontal, temporal, and parietal lobes. He was . . . [Full Text of this Article]

Differential Diagnosis

Infectious Diseases

Demyelinating Diseases

Inflammatory Diseases

Neuro-Behçet's Disease

Dr. David M. Greer's Diagnosis

Pathological Discussion

Discussion of Management

Anatomical Diagnosis


Source Information

From the Department of Neurology (D.M.G.), Division of Rheumatology, Allergy, and Immunology (R.P.F.), Division of Neuroradiology (J.R.), and the Department of Pathology (P.K.A.), Massachusetts General Hospital; and the Departments of Neurology (D.M.G.), Medicine (R.P.F.), Radiology (J.R.), and Pathology (P.K.A.), Harvard Medical School.



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