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Volume 360:2366-2367 May 28, 2009 Number 22
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Breast Cancer and Hormonal Therapy in Postmenopausal Women

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by Chlebowski, R. T.
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To the Editor: In their article on the Women's Health Initiative (WHI) study of combined hormone therapy, Chlebowski et al. (Feb. 5 issue)1 describe a marked decrease in the risk of breast cancer after the discontinuation of menopausal treatment. Using a similar approach, we investigated whether a decrease in risk was also seen in the French E3N cohort, in which the use of hormone therapy was self-reported biennially.2 Among postmenopausal respondents to the 1997–1998 questionnaire, women receiving combined hormone therapy and those who had never received hormone therapy were followed from January 1999 to the date of diagnosis of any . . . [Full Text of this Article]



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