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A principal feature of COPD is a
Mechanisms Leading to COPD
Step 1 — Initial Response to Cigarette Smoke
Step 2 — T-Cell Activation and Proliferation
Step 3 — Adaptive Immune Reaction
Evidence of Autoimmunity in COPD
Why Some Smokers Evade COPD
Conclusions
Source Information
From the Respiratory Division at Royal Victoria Hospital and the Meakins-Christie Laboratories in the Department of Medicine, McGill University, Montreal (M.G.C.); the Department of Cardiac, Thoracic, and Vascular Sciences, Section of Respiratory Diseases, University of Padua, Padua, Italy (M.S.); and Hospital Universitario Son Dureta, Fundación Caubet-Cimera, and the Centro de Investigacion Biomedica en Red (CIBER) Enfermedades Respiratorias, Mallorca, Balearic Islands, Spain (A.A.).
Address reprint requests to Dr. Cosio at McGill University, Respiratory Division, Royal Victoria Hospital, 687 Pine Ave., W., Rm. L4.11, Montreal, QC H3A 1A1, Canada, or at manuel.cosio@mcgill.ca.
Related Letters:
Immunologic Aspects of Chronic Obstructive Pulmonary Disease
Lamela J., Vega F.
Extract |
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N Engl J Med 2009;
361:1024, Sep 3, 2009.
Correspondence
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