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Previous Volume 361:1111-1112 September 10, 2009 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Cancer is believed to result from the acquisition of mutations and epigenetic changes that work collaboratively to induce the malignant growth of a cell. The field of cancer genomics has focused on defining the total complement of mutations in a cancer cell, with the belief that this information will drive personalized medicine through the development of improved diagnostic testing, prognostic and predictive markers, and ultimately new therapies directed against cancer-specific mutant proteins. Although 350 cancer genes have been identified to date (www.sanger.ac.uk/genetics/CGP/Census), we now sit at the beginning of a revolution in cancer genomics resulting from the systematic . . . [Full Text of this Article]

Source Information

From the Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN.

This article (10.1056/NEJMe0906090) was published on August 5, 2009, at NEJM.org.

This article has been cited by other articles:

• Mir, K. U. (2009). Sequencing Genomes: From Individuals to Populations. Brief Funct Genomic Proteomic 8: 367-378 [Abstract] [Full Text]