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Volume 361:1315-1316 September 24, 2009 Number 13
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Case 19-2009: Carcinoma of the Gastroesophageal Junction

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 by Kwak, E. L.
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To the Editor: In the Case Record of a 63-year-old woman with carcinoma of the gastroesophageal junction, Kwak et al. (June 18 issue)1 provide an excellent overview of the available evidence-based perioperative treatment options, including adjuvant chemoradiation, neoadjuvant chemoradiation, and perioperative chemotherapy. These therapies have never been directly compared and therefore are all reasonable treatment options.2,3,4 The authors are to be complimented for reaching out in their effort to provide guidance in selecting the optimal treatment approach in particular subgroups of patients (personalized medicine). However, we do not understand why they eventually treated the described patient with both perioperative chemotherapy . . . [Full Text of this Article]




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