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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 47-year-old man reports a 1-week history of diarrhea, with grossly bloody stools for the past 5 days. He reports no history of travel, contacts with sick persons, or underlying gastrointestinal disease. How should he be evaluated and treated for an infectious cause of his illness?
The Clinical Problem
Foodborne bacterial diarrhea is an emerging health threat that is attributable to the increased consumption of
Strategies and Evidence
Evaluation
Conditions Associated with Bacterial Diarrhea
Acute Watery Diarrhea
Dysentery
Food Poisoning
Traveler's Diarrhea
Nosocomial Diarrhea
Treatment
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the University of Texas School of Public Health, St. Luke's Episcopal Hospital, Baylor College of Medicine, and the Kelsey Research Foundation — all in Houston.
An audio version of this article is available at NEJM.org.
Address reprint requests to Dr. DuPont at 1200 Herman Pressler Dr., Suite 733, Houston, TX 77030, or at herbert.l.dupont@uth.tmc.edu.
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