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Case Records of the Massachusetts General Hospital
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Volume 361:1980-1989 November 12, 2009 Number 20
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Case 35-2009 — A 60-Year-Old Male Renal-Transplant Recipient with Renal Insufficiency, Diabetic Ketoacidosis, and Mental-Status Changes
Lindsey R. Baden, M.D., Subba R. Digumarthy, M.D., Alexander S.R. Guimaraes, M.D., Ph.D., and John A. Branda, M.D.

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Presentation of Case

Dr. Peter P. Moschovis (Medicine and Pediatrics): A 60-year-old man with diabetes mellitus and a history of renal transplantation was admitted to this hospital because of mental-status changes, diarrhea, renal insufficiency, diabetic ketoacidosis, and hypotension.

The patient was in his usual state of health, with chronic respiratory problems, until approximately 2 months before admission, when increasing fatigue, somnolence, and intermittent mild confusion developed, associated with diarrhea and decreasing glycemic control. Three weeks before admission, he was admitted to another hospital because of increasing orthopnea and paroxysmal nocturnal dyspnea. On examination, there were crackles in the bilateral midlung fields. The serum . . . [Full Text of this Article]

Differential Diagnosis

Transplant Recipients and Possible Infections

Community-Acquired Infections

Post-Transplantation Infections in Chronically Ill Patients

Post-Transplantation Malignant Conditions

Approach to Diagnosis

Summary

Clinical Diagnosis

Dr. Lindsey R. Baden's Diagnosis

Pathological Discussion

Anatomical Diagnosis


Source Information

From the Division of Infectious Disease, Brigham and Women's Hospital (L.R.B.); the Departments of Radiology (S.R.D., A.S.R.G.) and Pathology (J.A.B.), Massachusetts General Hospital; and the Departments of Medicine (L.R.B.), Radiology (S.R.D., A.S.R.G.), and Pathology (J.A.B.), Harvard Medical School.




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