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Previous Volume 361:1991-1993 November 12, 2009 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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In 1743, when disease was presumed to be astral in origin, European newspapers reported on a contagious influence (influenza in Italian) that was being visited on the citizens of Rome. Two hundred years later, Wilson Smith and colleagues would isolate an influenza A virus, one of the members of the orthomyxovirus family.¹ The key reservoirs of all influenza A viruses are migrating waterfowl, and intermittently, other hosts, such as pigs and people, are infected. Further classification of influenza A viruses is based on the specific hemagglutinin viral attachment spike and neuraminidase disengagement spike; the latter is cleaved when newly . . . [Full Text of this Article]

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From the Department of Internal Medicine, Virginia Commonwealth University, Richmond.

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