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Volume 361:720-721 August 13, 2009 Number 7
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Dipyridamole plus Aspirin and Hemodialysis Graft Patency

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by Dixon, B. S.
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To the Editor: Will the study by Dixon et al. (May 21 issue)1 change outcomes in clinical practice with respect to the use of dipyridamole plus aspirin for the treatment of hemodialysis graft stenosis? We suspect not. First, the external validity of the trial is difficult to assess, since the authors do not explain why a graft was chosen as the first access for nearly half the patients. Second, although treatment with dipyridamole plus aspirin modestly improved the predictably low primary patency of grafts,2 it is unlikely that such therapy actually reduced the risk of stenosis. Monthly flow monitoring was . . . [Full Text of this Article]



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