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Volume 361:722 August 13, 2009 Number 7
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Genomewide Association Studies of Stroke

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 by Ikram, M. A.
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To the Editor: The study by Ikram et al. (April 23 issue)1 was designed to provide information about the risk factors and prevalence of cardiovascular diseases, such as coronary heart disease and stroke. Risk factors and pathophysiological features of coronary heart disease and stroke are similar, and the two conditions frequently coexist. In one prospective study, coronary heart disease was present in 53% of patients with atherothrombotic stroke, and atherothrombotic stroke was present in 32% of patients with coronary heart disease.2 The basic assumption of the Cox proportional-hazards model is that the censoring of data from a study population occurs . . . [Full Text of this Article]




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