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A correction has been published: N Engl J Med 2009;361(15):1516.

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Shattuck Lecture
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Volume 361:878-887 August 27, 2009 Number 9
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The Hypertension Paradox — More Uncontrolled Disease despite Improved Therapy
Aram V. Chobanian, M.D.

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The treatment of hypertension has been one of medicine's major successes of the past half-century. The remarkable advances in therapy have provided the newfound capability for lowering blood pressure in almost every person with hypertension. Nevertheless, hypertension continues to be a major public health problem whose prevalence is increasing worldwide.1 Moreover, the number of people with uncontrolled blood pressure is also increasing, despite the therapeutic advances. Here, I discuss the factors responsible for this paradox and the strategies required for addressing the growing problem.

Early Approaches to Therapy

Hypertension is a major risk factor for cardiovascular and renal diseases, and early data indicate that . . . [Full Text of this Article]

Benefits of Antihypertensive-Drug Therapy

Evolving Approaches to Treatment

Lifestyle Modifications

Drugs

New Treatment Algorithm

Hypertension Control

Increase in the Prevalence of Hypertension


Source Information

From Boston University Medical Center, Boston.

This article (10.1056/NEJMsa0903829) was updated on October 7, 2009, at NEJM.org.

Address reprint requests to Dr. Chobanian at Boston University Medical Center, 650 Albany St., Boston, MA 02118, or at achob@bu.edu.


Related Letters:

The Hypertension Paradox
Schwarz U., Shil A. B., Spital A., Chobanian A. V.
Extract | Full Text | PDF  
N Engl J Med 2009; 361:2195-2197, Nov 26, 2009. Correspondence

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