A recent meta-analysis, report, and editorial all agreed withthe need for a randomized trial of percutaneous coronary intervention(PCI) as compared with coronary-artery bypass grafting (CABG)in patients with left main coronary artery disease.1,2,3 Themeta-analysis reported results of 16 observational studies on1278 patients undergoing PCI with drug-eluting stents for unprotectedleft main coronary artery disease.1 Mortality was 2.3% duringhospitalization and 5.5% at the time of last follow-up, at amedian of 10 months. Five randomized comparisons of PCI andCABG were noted to be ongoing, with combined enrollment goalsexceeding 2400 patients with unprotected left main . . . [Full Text of this Article]
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From the Department of Surgery, Duke Clinical Research Institute, Duke University Medical Center, Durham, NC.
This article (10.1056/NEJMe0802094) was published at www.nejm.org on March 31, 2008. It will appear in the April 24 issue of the Journal.
This article has been cited by other articles:
(2008). Stenting for Left Main Coronary Artery Disease?. JWatch General
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