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Published at www.nejm.org February 4, 2009 (10.1056/NEJMe0900361)

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Melamine, a synthetic nitrogenous product found in many industrial goods and even in fertilizer destined for use in growing crops for human consumption, was recently found to have been added to foods in China — including many different powdered infant formulas¹ — to increase their measured, but not biologically available, protein content. Melamine is largely not degraded in humans, although several other compounds (ammeline, ammelide, and cyanuric acid) may become cocontaminants during the manufacturing process, and the main route of excretion after absorption from the gastrointestinal tract appears to be through the urine.² The findings of acute kidney failure and . . . [Full Text of this Article]

Source Information

From the Feinberg School of Medicine, Northwestern University, Children's Memorial Hospital, Chicago.

This article (10.1056/NEJMe0900361) was published at NEJM.org on February 4, 2009. It will appear in the March 12 issue of the Journal.

This article has been cited by other articles:

• Ji, K., Zhu, S., Liu, Z., Dharnidharka, V. R., Hocking, B., Guan, N., Ding, J., Langman, C. B. (2009). Melamine-Contaminated Powdered Formula and Urolithiasis. NEJM 360: 2675-2678 [Full Text]