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Previous Volume 328:1571 May 27, 1993 Number 21 Next

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To the Editor: I do not know how many oncologists might use the dosages of chemotherapy described by McKeage et al. (Jan. 14 issue),¹ and thus how important this correction will be; however, the dosage intended was probably 100 mg of cisplatin and 500 to 600 mg of dacarbazine per square meter of body-surface area, given intravenously every three to four weeks, and not "three to four times weekly," which would prove lethal.

Klaus D. Hoffman, M.D.
6323 N. Fresno St.
Fresno, CA 93710

Editor's note: Dr. Hoffman is correct. The correct doses were 100 mg of cisplatin per square meter and 500 to 600 mg of dacarbazine per square meter, given intravenously once every three or four weeks.

References

1. McKeage MJ, Lorentzos A, Gore ME. Tamoxifen and chemotherapy for refractory metastatic malignant melanoma. N Engl J Med 1993;328:140-141. [Free Full Text]

Related Letters:

Tamoxifen and Chemotherapy for Refractory Metastatic Malignant Melanoma
McKeage M. J., Lorentzos A., Gore M. E., Cocconi G., Bella M., Bacchi M.
Extract | Full Text  
N Engl J Med 1993; 328:140-141, Jan 14, 1993. Correspondence

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