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Among the patients with normal serum alanine aminotransferase concentrations at six months, histologic improvement was observed in 78.6 percent of the patients in group 1 (22 of 28), 68.0 percent of those in group 2 (17 of 25), and 55.0 percent of those in group 3 (11 of 20). Among the patients with elevated serum alanine aminotransferase concentrations at six months, histologic improvement was observed in 60.7 percent of the patients in group 1 (17 of 28), 34.2 percent of those in group 2 (13 of 38), and 29.7 percent of those in group 3 (11 of 37). Among the patients with normal serum alanine aminotransferase concentrations at 18 months, histologic improvement was observed in 83.9 percent of the patients in group 1 (26 of 31), 72.2 percent of those in group 2 (13 of 18), and 57.9 percent of those in group 3 (11 of 19). Among the patients with elevated serum alanine aminotransferase concentrations at 18 months, histologic improvement was observed in 52.0 percent of those in group 1 (13 of 25), 37.8 percent of those in group 2 (17 of 45), and 28.9 percent of those in group 3 (11 of 38).
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