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Previous Volume 355:1958 November 9, 2006 Number 19 Next

PDF Perspective by White, N. J. Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Laufer, M. K.

Resistance to chloroquine is a major challenge in the treatment of falciparum malaria. In 1993, Malawi replaced chloroquine with sulfadoxine–pyrimethamine for malaria treatment. After the return of chloroquine-susceptible falciparum malaria to Malawi, investigators studied the reemergent clinical efficacy of chloroquine and found that it was approximately 99% effective.

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