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A healthy 70-year-old man presented with a 2-month history of painless swelling of his right upper and lower eyelids. The swelling had been treated with antibiotics, with no improvement. He had no history of ocular trauma and felt well. On examination, there was rubbery, painless thickening of the right eyelids (Panel A) with associated right preauricular lymphadenopathy. There was full range of ocular movement, and the right globe was unremarkable. The patient was afebrile, and the levels of inflammatory markers and the results of other blood tests were normal. Computed tomography of the orbit showed preseptal thickening of the right eyelids, with no associated muscle enlargement (Panel B, arrow). A biopsy showed a T-cell non-Hodgkin's lymphoma. The patient underwent chemotherapy, with rapid resolution of the eyelid swelling. Lymphoma should always be considered in patients with chronic painless lid swelling, especially in the elderly population, to avoid a delay in diagnosis.
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