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PERSPECTIVE ROUNDTABLE Previous Volume 360:e10 February 19, 2009 Number 8 Next

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In the international SYNTAX trial, 1800 patients with three-vessel or left-main coronary disease were randomly assigned to either revascularization with coronary-artery bypass grafting (CABG) or percutaneous coronary intervention involving drug-eluting stents. The need for repeat revascularization was significantly lower with CABG, but the risk of stroke was significantly higher — a tradeoff that must be considered in making clinical decisions regarding patients with advanced coronary disease. In a roundtable discussion moderated by Dr. Thomas Lee, cardiologists David Hillis and Elizabeth Nabel debate the implications of these findings for clinical practice.

View the video of this roundtable discussion, participate in the poll, and contribute your comments.

Related Letters:

Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting
Bhindi R., Figtree G. A., Edwards J. L., Brereton R. J.L., Misfeld M., Ross D. E., Shil A. B., Aung T., Strohm M. P., Bonvini R. F., Rapp F., Roffi M., Serruys P. W., Mohr F. W., the SYNTAX Investigators
Extract | Full Text | PDF  
N Engl J Med 2009; 360:2672-2675, Jun 18, 2009. Correspondence

This article has been cited by other articles:

• Smith, P. K. (2009). Treatment selection for coronary artery disease: the collision of a belief system with evidence.. Ann. Thorac. Surg. 87: 1328-1331 [Full Text]  
• Smith, P. K. (2009). Treatment selection for coronary artery disease: The collision of a belief system with evidence.. J. Thorac. Cardiovasc. Surg. 137: 1050-1053 [Full Text]