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Previous Volume 361:1613 October 15, 2009 Number 16 Next

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Estimation of the Warfarin Dose with Clinical and Pharmacogenetic Data . In Table 2 (page 758), the mean absolute errors in both cohorts should have been expressed as means with 95% confidence intervals rather than as means ±SE. The change affects the data in Table 2, the column heads, and the first footnote. In the first paragraph of the Doses Predicted by the Three Models subsection of Results (page 758), the parenthetical data should have read, "(8.5 mg per week [95% confidence interval {CI}, 8.0 to 9.0]) vs. 9.9 mg per week [95% CI, 9.3 to 10.4] and 13.0 mg per week [95% CI, 12.4 to 13.6], respectively; P<0.001 for both comparisons)." In addition, in the International Warfarin Pharmacogenetics Consortium pharmacogenetic dosing algorithm in Supplementary Appendix 2, the example given for CYP2C9 should have been represented as *C/*C instead of *C*C. The data have been validated and further examples for use added. The article has been corrected and Supplementary Appendix 2 replaced at NEJM.org.

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