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Previous Volume 328:726-728 March 11, 1993 Number 10 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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During the past 10 to 15 years, pathological and arteriographic studies have shown that Q-wave myocardial infarction is usually caused by an occlusive coronary arterial thrombus. Investigations have also shown that thrombolytic therapy can restore antegrade flow in the occluded artery, reduce the size of the infarct, and improve survival. Initially, thrombolytic agents were infused directly into the occluded coronary artery during cardiac catheterization, but later studies showed that intravenous administration offered similar efficacy without the delay, the need for angiographic equipment and skilled personnel, or the morbidity and mortality associated with emergency catheterization. Thus, effective therapy for evolving myocardial . . . [Full Text of this Article]

References

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• Khan, I. A. (2004). Initial Therapy for Acute Myocardial Infarction in the Real World. Chest 126: 331-333 [Full Text]  
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• Collins, R., Peto, R., Baigent, C., Sleight, P. (1997). Aspirin, Heparin, and Fibrinolytic Therapy in Suspected Acute Myocardial Infarction. NEJM 336: 847-860 [Full Text]  
• Spertus, J. A., Weiss, N. S., Every, N. R., Weaver, W. D., Myocardial Infarction Triage and Intervention Proj, (1995). The Influence of Clinical Risk Factors on the Use of Angiography and Revascularization After Acute Myocardial Infarction. Arch Intern Med 155: 2309-2316 [Abstract]  
• Ohnishi, Y., Butterfield, M. C., Saffitz, J. E., Sobel, B. E., Corr, P. B., Goldstein, J. A. (1995). Deleterious Effects of a Systemic Lytic State on Reperfused Myocardium : Minimization of Reperfusion Injury and Enhanced Recovery of Myocardial Function by Direct Angioplasty. Circulation 92: 500-510 [Abstract] [Full Text]  
• McMurray, J, Rankin, A (1994). Recent Advances: Cardiology - I: Treatment of myocardial infarction, unstable angina, and angina pectoris. BMJ 309: 1343-1350 [Full Text]  
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