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Correspondence
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Volume 328:814-815 March 18, 1993 Number 11
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Viral Culture of HIV in Neonates

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To the Editor: Burgard et al. (Oct. 22 issue)1 are to be congratulated on their use of very sensitive assays to detect infection with human immunodeficiency virus type 1 (HIV-1) in neonates and infants. However, in their Discussion the authors state that the frequency of transmission of this virus from infected women to their fetuses is not known and that there is an apparent absence of the viral genome in fetal tissues. The authors take this as evidence that vertical transmission occurs at birth and not prenatally. To support these conclusions, they cite three papers. However, other studies that do . . . [Full Text of this Article]

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