FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 328:856-860 March 25, 1993 Number 12 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Hysterectomy is second only to cesarean section as the most frequently performed major operation in the United States¹. Data from the National Hospital Discharge Survey (NHDS) indicate that approximately 590,000 hysterectomies are performed annually¹. Although there appears to be a downward trend in the rate since the mid-1980s, it is not yet known whether a true decline has occurred, because there have been recent changes in the NHDS sampling method^1,2. By the age of 60, over one third of U.S. women have undergone hysterectomy². The annual hospital costs for the operation currently exceed $5 billion.

There . . . [Full Text of this Article]

Uterine Leiomyomas

Dysfunctional Uterine Bleeding

Genital Prolapse

Endometriosis and Adenomyosis

Chronic Pelvic Pain

Pelvic Inflammatory Disease

Endometrial Hyperplasia

Cervical Intraepithelial Neoplasia, Invasive Uterine Cancer, and Other Cancers

Obstetrical Indications

Complications

Hysterectomy and Oophorectomy for the Prevention of Cancer

Conclusions

Source Information

From the Medical Service (K.J.C.) and the Vincent Memorial Gynecology Service (K.J.C., D.H.N., I.S.), Massachusetts General Hospital, and Harvard Medical School, Boston.

Address reprint requests to Dr. Schiff at the Vincent Memorial Gynecology Service, Massachusetts General Hospital, Boston, MA 02114.

References

Related Letters:

Indications for Hysterectomy
Oldenhave A., Gocze P. M., Patton W. W., Carlson K. J., Nichols D. H., Schiff I.
Extract | Full Text  
N Engl J Med 1993; 329:275-276, Jul 22, 1993. Correspondence

This article has been cited by other articles:

• Thakar, R., Ayers, S., Srivastava, R., Manyonda, I. (2008). Removing the Cervix at Hysterectomy: An Unnecessary Intervention?. Obstet Gynecol 112: 1262-1269 [Abstract] [Full Text]  
• Cooper, R, Lucke, J, Lawlor, D A, Mishra, G, Chang, J-H, Ebrahim, S, Kuh, D, Dobson, A (2008). Socioeconomic position and hysterectomy: a cross-cohort comparison of women in Australia and Great Britain. J. Epidemiol. Community Health 62: 1057-1063 [Abstract] [Full Text]  
• Kim, D.-c., Ramachandran, S., Baek, S.-h., Kwon, S.-H., Kwon, K.-Y., Cha, S.-D., Bae, I., Cho, C.-H. (2008). Induction of Growth Inhibition and Apoptosis in Human Uterine Leiomyoma Cells by Isoliquiritigenin. Reproductive Sciences 15: 552-558 [Abstract]  
• Yoshida, Y., Kurokawa, T., Sawamura, Y., Shinagawa, A., Tsujikawa, T., Okazawa, H., Tsuchida, T., Imamura, Y., Suganuma, N., Kotsuji, F. (2008). Comparison of 18F-FDG PET and MRI in Assessment of Uterine Smooth Muscle Tumors. JNM 49: 708-712 [Abstract] [Full Text]  
• Ren, X.-L., Zhou, X.-D., Zhang, J., He, G.-B., Han, Z.-H., Zheng, M.-J., Li, L., Yu, M., Wang, L. (2007). Extracorporeal Ablation of Uterine Fibroids With High-Intensity Focused Ultrasound: Imaging and Histopathologic Evaluation. J Ultrasound Med 26: 201-212 [Abstract] [Full Text]  
• Malik, S., Day, K., Perrault, I., Charnock-Jones, D.S., Smith, S. K. (2006). Reduced levels of VEGF-A and MMP-2 and MMP-9 activity and increased TNF-{alpha} in menstrual endometrium and effluent in women with menorrhagia. Hum Reprod 21: 2158-2166 [Abstract] [Full Text]  
• Al-Hendy, A., Salama, S. (2006). Gene therapy and uterine leiomyoma: a review. Hum Reprod Update 12: 385-400 [Abstract] [Full Text]  
• Boynton-Jarrett, R., Rich-Edwards, J., Malspeis, S., Missmer, S. A., Wright, R. (2005). A Prospective Study of Hypertension and Risk of Uterine Leiomyomata. Am J Epidemiol 161: 628-638 [Abstract] [Full Text]  
• Kim, B. Y., Cho, C.-H., Song, D.-K., Mun, K.-C., Suh, S.-I., Kim, S.-P., Shin, D.-H., Jang, B.-C., Kwon, T. K., Cha, S.-D., Bae, I., Bae, J. H. (2005). Ciglitizone inhibits cell proliferation in human uterine leiomyoma via activation of store-operated Ca2+ channels. Am. J. Physiol. Cell Physiol. 288: C389-C395 [Abstract] [Full Text]  
• Harmanli, O. H., Khilnani, R., Dandolu, V., Chatwani, A. J. (2004). Narrow Pubic Arch and Increased Risk of Failure for Vaginal Hysterectomy. Obstet Gynecol 104: 697-700 [Abstract] [Full Text]  
• Mhawech, P., Renaud, A., Sene, C., Ludicke, F., Herrmann, F., Szalay-Quinodoz, I., van den Bergh, H., Major, A.L. (2003). High efficacy of photodynamic therapy on rat endometrium after systemic administration of benzoporphyrin derivative monoacid ring A. Hum Reprod 18: 1707-1711 [Abstract] [Full Text]  
• Schaffer, J. I., Word, A. (2002). Hysterectomy -- Still a Useful Operation. NEJM 347: 1360-1362 [Full Text]  
• Pelage, J.-P., Laurent, A., Wassef, M., Bonneau, M., Germain, D., Rymer, R., Flaud, P., Martal, J., Merland, J.-J. (2002). Uterine Artery Embolization in Sheep: Comparison of Acute Effects with Polyvinyl Alcohol Particles and Calibrated Microspheres. Radiology 224: 436-445 [Abstract] [Full Text]  
• Materia, E, Rossi, L, Spadea, T, Cacciani, L, Baglio, G, Cesaroni, G, Arca, M, Perucci, C A (2002). Hysterectomy and socioeconomic position in Rome, Italy. J. Epidemiol. Community Health 56: 461-465 [Abstract] [Full Text]  
• Wu, X., Blanck, A., Norstedt, G., Sahlin, L., Flores-Morales, A. (2002). Identification of genes with higher expression in human uterine leiomyomas than in the corresponding myometrium. Mol Hum Reprod 8: 246-254 [Abstract] [Full Text]  
• WEAVER, F., HYNES, D., GOLDBERG, J. M., KHURI, S., DALEY, J., HENDERSON, W. (2001). Hysterectomy in Veterans Affairs Medical Centers. Obstet Gynecol 97: 880-884 [Abstract] [Full Text]  
• Bischof, J. C., Fahssi, W. M., Smith, D., Nagel, T., Swanlund, D. J. (2001). A parametric study of freezing injury in ELT-3 uterine leiomyoma tumour cells. Hum Reprod 16: 340-348 [Abstract] [Full Text]  
• Adolfsson, P. I., Haug, I., Berg, G., Svensson, S. P.S. (2000). Changes in {beta}2-adrenoceptor expression and in adenylyl cyclase and phosphodiesterase activity in human uterine leiomyomas. Mol Hum Reprod 6: 835-842 [Abstract] [Full Text]  
• Pelage, J.-P., Le Dref, O., Soyer, P., Kardache, M., Dahan, H., Abitbol, M., Merland, J.-J., Ravina, J.-H., Rymer, R. (2000). Fibroid-related Menorrhagia: Treatment with Superselective Embolization of the Uterine Arteries and Midterm Follow-up. Radiology 215: 428-431 [Abstract] [Full Text]  
• Laughlin, G. A., Barrett-Connor, E., Kritz-Silverstein, D., von Mühlen, D. (2000). Hysterectomy, Oophorectomy, and Endogenous Sex Hormone Levels in Older Women: The Rancho Bernardo Study. J. Clin. Endocrinol. Metab. 85: 645-651 [Abstract] [Full Text]  
• Tsibris, J. C. M., Porter, K. B., Jazayeri, A., Tzimas, G., Nau, H., Huang, H., Kuparadze, K., Porter, G. W., O'Brien, W. F., Spellacy, W. N. (1999). Human Uterine Leiomyomata Express Higher Levels of Peroxisome Proliferator-activated Receptor {{gamma}}, Retinoid X Receptor {{alpha}}, and all-trans Retinoic Acid Than Myometrium. Cancer Res. 59: 5737-5744 [Abstract] [Full Text]  
• Murase, E., Siegelman, E. S., Outwater, E. K., Perez-Jaffe, L. A., Tureck, R. W. (1999). Uterine Leiomyomas: Histopathologic Features, MR Imaging Findings, Differential Diagnosis, and Treatment. RadioGraphics 19: 1179-1197 [Abstract] [Full Text]  
• ROWE, M. K., KANOUSE, D. E., MITTMAN, B. S., BERNSTEIN, S. J. (1999). Quality of Life Among Women Undergoing Hysterectomies. Obstet Gynecol 93: 915-921 [Abstract] [Full Text]  
• Dolan, J. G., Howard, F. M. (1999). A Survey of Gynecologists' Attitudes Regarding Decision Making in the Management of Non-cancerous Conditions That Frequently Result in Hysterectomy. Med Decis Making 19: 186-192 [Abstract]  
• Shekelle, P. G., Kahan, J. P., Bernstein, S. J., Leape, L. L., Kamberg, C. J., Park, R.E. (1998). The Reproducibility of a Method to Identify the Overuse and Underuse of Medical Procedures. NEJM 338: 1888-1895 [Abstract] [Full Text]  
• Alexander, D. A, Naji, A. A., Pinion, S. B, Mollison, J., Kitchener, H. C, Parkin, D. E, Abramovich, D. R, Russell, I. T (1996). Randomised trial comparing hysterectomy with endometrial ablation for dysfunctional uterine bleeding: psychiatric and psychosocial aspects. BMJ 312: 280-284 [Abstract] [Full Text]  
• Arndt, M., Bradbury, R. C., Golec, J. (1995). Indications for Hysterectomy: Variation within and Across Hospitals. Med Care Res Rev 52: 342-363 [Abstract]  
• Oldenhave, A., Gocze, P. M., Patton, W. W., Carlson, K. J., Nichols, D. H., Schiff, I. (1993). Indications for Hysterectomy. NEJM 329: 275-276 [Full Text]