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A correction has been published: N Engl J Med 1996;335(23):1771.

Original Article
Brief Report
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Volume 328:1007-1009 April 8, 1993 Number 14
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Disseminated Osteomyelitis from Mycobacterium ulcerans after a Snakebite
Michael Hofer, Bernard Hirschel, Philip Kirschner, Maurice Beghetti, Andre Kaelin, Clair-Anne Siegrist, Susanne Suter, Andreas Teske, and Erik C. Bottger

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 by Hu, L. B.
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Atypical mycobacteria have been widely recognized as human pathogens only since the 1950s1. Multiple organs can be involved, in particular the skin and bones. However, disseminated infection is usually observed only in immunodeficient hosts. We describe a boy with an apparently normal immune system, who nevertheless had debilitating multifocal osteomyelitis associated with a growth-deficient acid-fast microorganism. The microorganism was identified as Mycobacterium ulcerans by DNA amplification and subsequent determination of the nucleic acid sequence.

Case Report

The patient, born in November 1985, was the fourth child of a farmer from West Africa. In 1989 he was bitten on his right leg . . . [Full Text of this Article]

Discussion


Source Information

From the Departement de Pediatrie (M.H., C.-A.S., S.S.), Division de maladies infectieuses (B.H.), and Unite d'orthopedie pediatrique (M.B., A.K.), Hopital Cantonal Universitaire, Geneva, Switzerland, and the Institut fur Medizinische Mikrobiologie, Medizinische Hochschule, Hannover, Germany (P.K., A.T., E.C.B.).

Address reprint requests to Dr. Hirschel at the Division of Infectious Diseases, Hopital Cantonal Universitaire, CH-1211 Geneva 4, Switzerland.

References


Related Letters:

Mycobacterium ulcerans and Osteomyelitis
Kristjansson M., Arbeit R. D., Weed H. G., Hirschel B., Bottger E.
Extract | Full Text  
N Engl J Med 1993; 329:582-583, Aug 19, 1993. Correspondence

Mycobacterium ulcerans Osteomyelitis: A Closer Look at the X-Ray Films
Hu L. B., Hofer M., Hirschel B.
Extract | Full Text  
N Engl J Med 1996; 335:1771-1772, Dec 5, 1996. Correspondence

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