Disseminated Osteomyelitis from Mycobacterium ulcerans after a Snakebite
Michael Hofer, Bernard Hirschel, Philip Kirschner, Maurice Beghetti, Andre Kaelin, Clair-Anne Siegrist, Susanne Suter, Andreas Teske, and Erik C. Bottger
Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.
Atypical mycobacteria have been widely recognized as human pathogensonly since the 1950s1. Multiple organs can be involved, in particularthe skin and bones. However, disseminated infection is usuallyobserved only in immunodeficient hosts. We describe a boy withan apparently normal immune system, who nevertheless had debilitatingmultifocal osteomyelitis associated with a growth-deficientacid-fast microorganism. The microorganism was identified asMycobacterium ulcerans by DNA amplification and subsequent determinationof the nucleic acid sequence.
Case Report
The patient, born in November 1985, was the fourth child ofa farmer from West Africa. In 1989 he was bitten on his rightleg . . . [Full Text of this Article]
Discussion
Source Information
From the Departement de Pediatrie (M.H., C.-A.S., S.S.), Division de maladies infectieuses (B.H.), and Unite d'orthopedie pediatrique (M.B., A.K.), Hopital Cantonal Universitaire, Geneva, Switzerland, and the Institut fur Medizinische Mikrobiologie, Medizinische Hochschule, Hannover, Germany (P.K., A.T., E.C.B.).
Address reprint requests to Dr. Hirschel at the Division of Infectious Diseases, Hopital Cantonal Universitaire, CH-1211 Geneva 4, Switzerland.
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