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Previous Volume 328:1017-1022 April 8, 1993 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The term "chronic obstructive pulmonary disease" (COPD) refers to a spectrum of chronic respiratory diseases characterized by cough, sputum production, dyspnea, airflow limitation, and impaired gas exchange. Most often associated with cigarette smoking, COPD is estimated to affect at least 15 million Americans and is the fifth leading cause of death in the United States¹. Indeed, the death rate has risen by 22 percent in the past decade, and the mortality rate 10 years after diagnosis is greater than 50 percent². Although many issues remain unresolved, considerable advances have been made in the care of patients with this . . . [Full Text of this Article]

Education

Retarding the Progression of Airflow Limitation

Minimizing Airflow Limitation

Reduced Production of Secretions

Increased Elimination of Secretions

Bronchodilation

Sympathomimetic Agents

Anticholinergic Agents

Theophylline

Corticosteroids

Correcting Secondary Physiologic Alterations

Hypoxemia

Pulmonary Hypertension and Cor Pulmonale

Hypercapnia

Optimizing Functional Capability

Exercise Conditioning

Upper-Extremity Training

Respiratory-Muscle Training

Respiratory-Muscle Rest

Dyspnea

Nutrition

Physical and Occupational Therapy

Psychosocial Rehabilitation

Other Issues in Treatment

₁-Antitrypsin Augmentation

Bullectomy

Lung Transplantation

Conclusion

Source Information

From the Pulmonary Science Division, Departments of Medicine, University of Colorado Health Sciences Center and the National Jewish Center for Immunology and Respiratory Medicine, Denver.

Address reprint requests to Dr. Ferguson at the National Jewish Center, 1400 Jackson St., Denver, CO 80206.

References

Related Letters:

Management of Chronic Obstructive Pulmonary Disease
Matz R., Chinet T. C., Kinshuck D., Malik T., Mulleneisen N. K., Ferguson G. T., Cherniack R. M.
Extract | Full Text  
N Engl J Med 1993; 329:967-968, Sep 23, 1993. Correspondence

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