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Previous Volume 328:1045-1046 April 8, 1993 Number 14 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The article by Canellos et al. (Nov. 19 issue)¹ makes an important contribution to the longstanding controversy^2,3 about the optimal drug regimen for advanced Hodgkin's disease. On the basis of their investigation, the authors conclude that treatment with doxorubicin, bleomycin, vinblastine, and dacarbazine (ABVD) is superior to treatment with the older combination of mechlorethamine, vincristine, procarbazine, and prednisone (MOPP), a conclusion that has been in the wind for some time. Because a definitive study is likely to define standard practice, the new investigation deserves close scrutiny.

The most worrisome complication of ABVD therapy is the pulmonary toxicity, . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Tesch, H., Diehl, V., Lathan, B., Hasenclever, D., Sieber, M., Ruffer, U., Engert, A., Franklin, J., Pfreundschuh, M., Schalk, K.P., Schwieder, G., Wulf, G., Dolken, G., Worst, P., Koch, P., Schmitz, N., Bruntsch, U., Tirier, C., Muller, U., Loeffler, M. (1998). Moderate Dose Escalation for Advanced Stage Hodgkin's Disease Using the Bleomycin, Etoposide, Adriamycin, Cyclophosphamide, Vincristine, Procarbazine, and Prednisone Scheme and Adjuvant Radiotherapy: A Study of the German Hodgkin's Lymphoma Study Group. Blood 92: 4560-4567 [Abstract] [Full Text]  
• Multani, P. S., Grossbard, M. L. (1996). Staging Laparotomy in the Management of Hodgkin's Disease: Is it Still Necessary?. The Oncologist 1: 41-55 [Abstract] [Full Text]