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Previous Volume 328:1127-1128 April 15, 1993 Number 15 Next

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To the Editor: Gordeuk et al. (Nov. 19 issue)¹ suggest that iron deficiency may protect against malaria. It does not. Of 101 children with malaria and anemia studied in Kenya, 15 had iron deficiency². The development of malaria was not impaired because plasmodia obtain their iron from hemoglobin in iron-deficient red cells³.

Ten of the children in Kenya had sickle cell disease,² which, like thalassemia, is usually protective against malaria³. They had been taking folate supplements because of the increased need for folate in chronic hemolytic anemias and thus did not have the folate deficiency otherwise common . . . [Full Text of this Article]

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