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Previous Volume 328:1193-1195 April 22, 1993 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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It would seem that a relatively simple question -- "Does amniotomy have an important effect on the course of labor at term?" -- should be relatively easy to answer, but this has not proved to be the case. The routine use of amniotomy to hasten labor has engendered controversy in the obstetrical community since its introduction into clinical practice by Kreis in 1928¹. Almost 50 years later, recognition of the role of prostaglandins in both initiating labor and mediating cervical dilatation provided a physiologic basis for the observed effects of amniotomy. The concentration of prostaglandins E₂ and F₂ in . . . [Full Text of this Article]

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