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Previous Volume 328:1323-1332 May 6, 1993 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The importance of neutropenia in the risk of serious infection in patients with cancer who are receiving cytotoxic chemotherapy was first recognized nearly 30 years ago¹. Since then, considerable progress has been made in the management of fever and neutropenia in both adults and children, resulting in improved survival rates not only for these patients but also for other immunosuppressed patients, including those undergoing organ or bone marrow transplantation and those with bone marrow failure or human immunodeficiency virus (HIV) infection^2,3.

Some of the current principles for the management of fever in patients with neutropenia are outlined in . . . [Full Text of this Article]

The Foundations of Empirical Therapy

Modifications of Initial Management and the Acceleration of Neutrophil Recovery

Changes in the Predominant Organisms

Patients at Risk for Infection

Diagnostic Methods and the Frequency with Which Infection Is Identified

Antimicrobial Therapy in Patients with Neutropenia

Care of Patients with Indwelling Catheters

Improvement of Host Defenses with Hematopoietic Growth Factors

Goals for the Future

Source Information

From the Pediatric Branch, National Cancer Institute, Bldg. 10, Rm. 13N240, Bethesda, MD 20892, where reprint requests should be addressed to Dr. Pizzo.

References

Related Letters:

Fever in Patients with Neutropenia
Paschal B. R., Gradon J. D., Rolston K. V.I., Rubenstein E. B., Pizzo P. A.
Extract | Full Text  
N Engl J Med 1993; 329:1279-1280, Oct 21, 1993. Correspondence

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