FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 328:142-143 January 14, 1993 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

To the Editor: Pressed by the increasing shortage of human organs, we are rapidly moving toward the use of xenografts from pigs or nonhuman primates. We must ask whether endogenous animal retroviruses pose any public health risk when transplanted into a human host.

Endogenous porcine retroviruses are not believed to undergo acute transformation; however, the expression of retroviruses has been associated with the development of leukemia and lymphoma in pigs¹. Little is known about their structure, their similarities to other retroviruses, or the mechanism of their association with malignant diseases. Since these viral genomes are coded in the genomic . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Schillaci, M. A., Waitzkin, H., Carson, E. A., Lopez, C. M., Boehm, D. A., Lopez, L. A., Mahoney, S. F. (2004). Immunization Coverage and Medicaid Managed Care in New Mexico: A Multimethod Assessment. Ann Fam Med 2: 13-21 [Abstract] [Full Text]  
• Clark, M. A. (1999). This Little Piggy Went to Market: The Xenotransplantation and Xenozoonose Debate. J Law Med Ethics 27: 137-152  
• Chapman, L. E., Folks, T. M., Salomon, D. R., Patterson, A. P., Eggerman, T. E., Noguchi, P. D. (1995). Xenotransplantation and Xenogeneic Infections. NEJM 333: 1498-1501 [Full Text]