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Previous Volume 328:1487-1489 May 20, 1993 Number 20 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This issue of the Journal contains two important reports of large-scale prospective studies, one in men¹ and one in women,² showing that the use of large doses of vitamin E supplements is associated with a significantly decreased risk of coronary heart disease. The study populations were enormous -- almost 40,000 men and more than 80,000 women -- and the participants were followed for four and eight years, respectively. The studies were very carefully conducted: there was more than 95 percent follow-up, independent validation of the dietary questionnaires, and careful documentation of end points. In both studies the benefit of vitamin . . . [Full Text of this Article]

References

Related Letters:

Vitamin E and the Risk of Coronary Disease
O'Keefe J. H., Lavie C. J., Steiner M., Powell L. H., Black H. R., Sullivan J. L., Stampfer M. J., Rimm E. B., Willett W. C., Steinberg D.
Extract | Full Text  
N Engl J Med 1993; 329:1424-1426, Nov 4, 1993. Correspondence

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