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Previous Volume 328:1568-1569 May 27, 1993 Number 21 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Dr. Groop and colleagues (Jan. 7 issue)¹ reported that, in Finland, the A₂ allele of the XbaI polymorphism of the glycogen synthase gene is associated with non-insulin-dependent diabetes mellitus (NIDDM) and identifies a subgroup of patients with a strong family history of diabetes, a high prevalence of hypertension, and insulin resistance. We studied this polymorphism in 231 unrelated white patients with NIDDM from multiplex French families with the disease by polymerase-chain-reaction (PCR) amplification of the glycogen synthase gene using primers kindly provided by Dr. Groop. The presence of the A₁ and A₂ alleles was compared in the . . . [Full Text of this Article]

References

This article has been cited by other articles:

• St-Onge, J., Joanisse, D. R., Simoneau, J.-A. (2001). The Stimulation-Induced Increase in Skeletal Muscle Glycogen Synthase Content Is Impaired in Carriers of the Glycogen Synthase XbaI Gene Polymorphism. Diabetes 50: 195-198 [Abstract] [Full Text]  
• Schalin-Jantti, C., Nikula-Ijas, P., Huang, X., Lehto, M., Knudsen, P., Syvanne, M., Lehtovirta, M. T., Tikkanen, T., Tikkanen, I., Groop, L. C. (1996). Polymorphism of the Glycogen Synthase Gene in Hypertensive and Normotensive Subjects. Hypertension 27: 67-71 [Abstract] [Full Text]